factors effecting erythropoiesis
BY: FARAH IDAYU BINTI SAMSUDIN
VITAMIN
did you ever remember the day when we are being forced and asked forcefully by our parents to eat lots lots and lots of vitamins during our childhood?
i mean this vitamin for example ⬇
I bet yall only think that vitamin are only good for our skin and our immune system
but now let me tell you that
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It also help in ERYTHROPOEISIS !!! Ok dont be confused because im gonna explain about that right now . Heres are some examples of vitamins that play role in erythtropoiesis.
Cyanocobalamin
Dont be afraid with the name, it might sound so terrifying (because it sounds so chemical) but actually they are called Vitamin B12
Example of food that contain vitamin B12 are eggs,milk,cheese, meat and poultry. Vitamin B12 is stored mostly in liver and in small quantity of muscle. However, when it is necessary, it will be transported to the bone marrow to promote the maturation of red blood cell.
Besides, the vitamin B12 also helps in erythtropoiesis as it is essential for formation of thymidine trihosphate and for synthesis of DNA in the red blood cell. However, it deficiency may lead to failure in maturation of cell and reduction in cell division.
Example of food that contain vitamin B12 are eggs,milk,cheese, meat and poultry. Vitamin B12 is stored mostly in liver and in small quantity of muscle. However, when it is necessary, it will be transported to the bone marrow to promote the maturation of red blood cell.
Besides, the vitamin B12 also helps in erythtropoiesis as it is essential for formation of thymidine trihosphate and for synthesis of DNA in the red blood cell. However, it deficiency may lead to failure in maturation of cell and reduction in cell division.
Vitamin C
yes we all know that fruits are the example of vitamin c but before we start, let me ask you a simple riddle about fruits.
what is the fruit named by a tree and different fruit ? *keep reading this blog to know the answer
ok back to how vitamin c effect erythropoiesis. In this matter, vitamin C helps in the absorption of iron besides vitamin c is also needed to reduce ferric to ferrous form.
Riboflavin
Its less terrifying this time right because i accidentally choose this picture (bet yall see that picture first rather than the title right)
Milk, cheese, liver, vegetable leaf, legumes, mushrooms, and almonds are the examples of food that contain this vitamin. In erythropoiesis, vitamin B2 helps in heme formation and it also associate in the cell growth and division.
before we proceed, let me tell you the answer for the previous riddle. the answer is PINEAPPLE.PINE= tree and APPLE= different fruit. if you got the correct answer, give yourself around of applause !!!!
MINERALS
The minerals like iron and copper and pivotal in making healthy red blood cells.
Iron
Food such as legumes, grains, egg yolk and meat are rich in iron .
Iron makes up the part of heme. The iron molecule in each heme group directly bind and carries oxygen. If you don't eat enough iron, you cannot produce enough heme to make functional red blood cells.
Iron makes up the part of heme. The iron molecule in each heme group directly bind and carries oxygen. If you don't eat enough iron, you cannot produce enough heme to make functional red blood cells.
Copper
Cobalt
PROTEINS
Uptake of protein is also affect erythtropoiesis. For example, adequate protein diet will cause more formation of globin. Thus this will increase the production of red blood cell.
So we need to consume more protein from food like poultry,milk,meat and eggs to increase production of red blood cell.
HORMONES
there are several hormone that affect erythtropoiesis:
- Testosterone
- Growth Hormone
- Thyroid hormone
- Cortisol
- Adrenocorticotrophic hormone (ACTH)
This is because this hormones increase the rate of metabolism of body thus it also will increase the production of red blood cell in the body
OTHER CONDITION
Have you guys ever be in the situation where youre face become red or blushed. we all have experience that right. well dont be afraid, it actually means that our body are producing more red blood cell at that very moment. There are several other condition that can affect erythtropoiesis.
For example, when we are doing physical activities, our face will automatically become red because our body produce more red blood cell to enable efficient oxygen supply to whole parts of the body.
or when someone makes you feel excited until you blushed as red as a tomato
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or when you are pregnant
or when you are on menstruation (dont mess up with them)
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